![]() Details of internal structure were better assessed at 7 T compared to 3 T, with 4/7 lesions (57%) displaying numerous internal details compared to 0/7 lesions (0%) at 3 T (P=0.10). Delineation of lesion margins was better scored at 7 T compared to 3 T with 3/7 lesions (43%) scored as very well delineated on 7 T compared to 0/7 lesions (0%) at 3 T, although the difference was not significant (P=0.34). Orbital lesion conspicuity was better scored at 7 T compared to 3 T MRI, with 3/7 lesions (43%) scored as very conspicuous at 7 T compared to 0/7 lesion (0%) at 3 T, although the difference was not significant (P=0.16). Comparison between both datasets was made using Fisher exact test.RESULTS: Seven patients (4 women, 3 men) with a median age of 52 years were enrolled. They assessed general characteristics of each orbital lesion as well as image quality and presence of artifacts. Two neuroradiologists, blinded to all data, read both datasets independently and randomly. The purpose of this study was to compare 3 Tesla (T) to 7 T magnetic resonance imaging (MRI) for characterizing orbital lesions.MATERIALS AND METHODS: This prospective single-center study enrolled participants presenting with orbital lesions from May to October 2019, who underwent both 7 T and 3 T MRI examinations. PURPOSE: Characterizing orbital lesions remains challenging with imaging. Diagnostic and interventional imaging Lecler, A., Duron, L., Charlson, E., Kolseth, C., Kossler, A. Comparison between 7 Tesla and 3 Tesla MRI for characterizing orbital lesions.Cognitive impairment related to volume loss of the anterior group.Thalamic nuclei closest to the third ventricle are more affected, with cognitive consequences. Medial and posterior thalamic groups were significantly more affected than anterior and lateral groups. ![]() Volumes of thalamic nuclei were compared according to clinical phenotypes and cognitive profile.T1- and WMn-MPRAGE provided comparable segmentations (0.84 ± 0.13 < volume-similarity-index < 0.95 ± 0.03). T1-based thalamic segmentation was compared with the reference WMn-MPRAGE method. Investigating differential vulnerability of thalamic nuclei in multiple sclerosis (MS).In a secondary analysis of prospectively collected datasets, we pooled 136 patients with MS or clinically isolated syndrome and 71 healthy controls all scanned with conventional 3D-T1 and white-matter-nulled magnetization-prepared rapid gradient echo (WMn-MPRAGE) and tested for cognitive performance. Vice Provost for Undergraduate Education.Office of Vice President for Business Affairs and Chief Financial Officer.Office of VP for University Human Resources.Stanford Woods Institute for the Environment.Stanford Institute for Economic Policy Research (SIEPR).Institute for Stem Cell Biology and Regenerative Medicine.Institute for Human-Centered Artificial Intelligence (HAI).Institute for Computational and Mathematical Engineering (ICME).Freeman Spogli Institute for International Studies.Stanford Doerr School of Sustainability.
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